The hydroclimate history of the late Quaternary Lake Kinneret watershed was explored through studies of sediment cores drilled at several sites. The drilling recovered laminated sedimentary sequences comprising primary calcite and silty detritus, and containing ostracods and diatoms. The cores span the time intervals of ~ 28-22 ka (Ohalo-II shore), ~ past 25 kyrs (core KIN2, Station A) and past ~ 23 kyr (core SOG3, off Ginosar). The primary calcite was deposited from the lake’s water. Chemical compositions (e.g., concentrations and elemental ratios such as Sr/Ca, U/Ca, and Mg/Ca) and 87Sr/86Sr isotope ratios were used to quantify the contributions of fresh and brines to the lake and to trace their temporal changes. Between ~ 28-25 ka, Lake Kinneret and Lake Lisan reached their highest stands (~ 170 m bmsl) and merged. At ~ 24 ka, both lakes retreated due to arid conditions in their watershed that coincided with the cold Heinrich stadial HE2 in the North Atlantic. At ~ 23-22 ka, the late Paleolithic Kebaran people established a lakeshore camp at the retreating Ohalo shore. After 22 ka lake’s water rose above the Paleolithic site. The Ohalo shore was rapidly buried under fine lake sediments, creating waterlogged, anaerobic conditions that helped preserve the site (e.g., hut floors, plant fibers, and seeds). Ostracod shells from Cursi Basin (KIN2) and Ohalo shore of MIS2 (high-stand) ages show 87Sr/86Sr ratios of 0.7079±1 and Sr/Ca(eq) ratios ~ 0.007-0.009, distinctly different from the ratios of modern Lake Kinneret (~0.7076 and ~ 0.006, respectively). The KIN2 ratios could indicate an enhanced input of Lake Lisan Ca-Chloride brine during the high stand period, allowing the Lisan brine to ingress into the deep basin of Lake Kinneret (Cursi Basin). This scenario is corroborated by recent porewater data that will be discussed in the Kinneret session.